Shutting down Wnt signal-activated cancer

Sharp cell type boundaries emerge from coordinated morphogen signaling.

bioRxiv : the preprint server for biology·2026

Targeting β-catenin degradation with GSK3β inhibitors induces cell death in acute lymphoblastic leukemia.

Nature cancer·2026

Interaction of Wnt and SHH gradients synchronizes cell cycle exit and differentiation.

bioRxiv : the preprint server for biology·2025

Dedifferentiation maintains melanocyte stem cells in a dynamic niche.

Nature·2023

Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies.

bioRxiv : the preprint server for biology·2023

Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients.

Developmental cell·2022

Rare variant effect estimation and polygenic risk prediction.

Nature genetics·2026

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

Nature genetics·2026

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Nature genetics·2026

Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection.

Nature genetics·2026

hnRNPK condensates facilitate enhancer-promoter looping and RNA polymerase II recruitment.

Nature genetics·2026

Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer's disease.

Nature genetics·2026

Lycium barbarum glycopeptide protects against inherited retinal degeneration in rd10 mice by regulating phototransduction and neuroinflammatory pathways.

Neural regeneration research·2026

Neuronal Ddit4 overexpression in the medial prefrontal cortex reduces synaptic density and impairs cognitive function in mice.

eNeuro·2026

Exosome therapy for knee osteoarthritis: a network meta-analysis based on rat models.

Stem cells translational medicine·2026

Tobacco and Marijuana Induce Adverse Effects on Cardiac Function and Platelet Activity and Reduce Tissue Preservation Following Myocardial Infarction.

American journal of physiology. Heart and circulatory physiology·2026

Danburstotug, an anti-PD-L1 antibody, in relapsed/refractory extra-nodal natural killer/T-cell lymphoma: The phase 2 DISTINKT study.

British journal of haematology·2026

Targeting AHNAK ameliorates osteonecrosis of the femoral head and affects adipogenic pathways involving Smad/PPARγ.

Bone & joint research·2026

Related Experiment Videos

Shutting down Wnt signal-activated cancer

Related Concept Videos

Sharp cell type boundaries emerge from coordinated morphogen signaling.

Targeting β-catenin degradation with GSK3β inhibitors induces cell death in acute lymphoblastic leukemia.

Interaction of Wnt and SHH gradients synchronizes cell cycle exit and differentiation.

Dedifferentiation maintains melanocyte stem cells in a dynamic niche.

Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies.

Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients.

Rare variant effect estimation and polygenic risk prediction.

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection.

hnRNPK condensates facilitate enhancer-promoter looping and RNA polymerase II recruitment.

Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer's disease.

Lycium barbarum glycopeptide protects against inherited retinal degeneration in rd10 mice by regulating phototransduction and neuroinflammatory pathways.

Neuronal Ddit4 overexpression in the medial prefrontal cortex reduces synaptic density and impairs cognitive function in mice.

Exosome therapy for knee osteoarthritis: a network meta-analysis based on rat models.

Tobacco and Marijuana Induce Adverse Effects on Cardiac Function and Platelet Activity and Reduce Tissue Preservation Following Myocardial Infarction.

Danburstotug, an anti-PD-L1 antibody, in relapsed/refractory extra-nodal natural killer/T-cell lymphoma: The phase 2 DISTINKT study.

Targeting AHNAK ameliorates osteonecrosis of the femoral head and affects adipogenic pathways involving Smad/PPARγ.

Related Experiment Videos

Shutting down Wnt signal-activated cancer

Related Concept Videos

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