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[Plexiform neurofibroma in the gingiva].

Hatice Savaş1, Aydin Karabacakoğlu, Serdar Karaköse

  • 1Selçuk Universitesi Meram Tip Fakültesi, Radyoloji Anabilim Dali, Konya, Turkey.

Tanisal Ve Girisimsel Radyoloji : Tibbi Goruntuleme Ve Girisimsel Radyoloji Dernegi Yayin Organi
|April 1, 2004
PubMed
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Neurofibromatosis type 1, a common genetic disorder, rarely affects the gums. This study highlights rare radiological findings of diffuse, unilateral gingival involvement in three patients with plexiform neurofibroma.

Area of Science:

  • Genetics
  • Oncology
  • Radiology

Background:

  • Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder affecting multiple systems.
  • NF1 commonly impacts the skeletal, central nervous, ocular, endocrine, and cardiovascular systems.
  • Gingival involvement in NF1 is exceptionally rare.

Purpose of the Study:

  • To report and describe the radiological findings of rare gingival involvement in patients with NF1.
  • To increase awareness of plexiform neurofibromas presenting as diffuse, unilateral gingival masses.

Main Methods:

  • Retrospective review of radiological findings.
  • Case series of three patients diagnosed with NF1 and exhibiting gingival abnormalities.

Main Results:

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  • All three patients presented with diffuse, unilateral gingival enlargement.
  • Radiological imaging revealed features consistent with plexiform neurofibroma of the gingiva.
  • Detailed radiological characteristics of the gingival neurofibromas were documented.

Conclusions:

  • Gingival manifestation, though rare, can occur in Neurofibromatosis type 1.
  • Plexiform neurofibroma should be considered in the differential diagnosis of diffuse gingival enlargement, especially in patients with NF1.
  • Radiological assessment is crucial for characterizing these rare presentations.