Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postoperative endocrine function in patients with surgically treated thyrotoxicosis.

Ranjiv Sivanandan1, Lay Guat Ng, Lay Wai Khin

  • 1Department of Surgery, Singapore General Hospital, Singapore. ranjiv@ohns.stanford.edu

Head & Neck
|April 1, 2004
PubMed
Summary

Predicting endocrine function after thyrotoxicosis surgery is challenging. Long-term follow-up is crucial as hypothyroidism develops early, and recurrent hyperthyroidism increases over time.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Public knowledge and perceptions of kidney transplantation in Singapore: findings from a pilot survey.

Singapore medical journal·2026
Same author

An evidence-based review by the EAU Endourology on standard practices and future directions for ureteral stents in transplant patients.

World journal of urology·2026
Same author

How threshold customisation affects the performance of a multiclass X-ray AI model for primary care triage: a retrospective study.

BMJ open·2026
Same author

Ureteroscopy for renal allograft lithiasis: institutional experience and global insights from a systematic review.

Translational andrology and urology·2026
Same author

Intravenous immunoglobulin and mammalian target of rapamycin inhibitors for treatment of BK virus infections in kidney transplantation: a systematic review.

Clinical transplantation and research·2025
Same author

Cone beam CT for paranasal sinus and temporal bone: A cost-benefit analysis in Singapore.

Annals of the Academy of Medicine, Singapore·2025

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Thyroid Surgery

Background:

  • Predicting endocrine function after thyrotoxicosis surgery is complex.
  • Assessing operative morbidity and long-term thyroid function is essential.

Purpose of the Study:

  • To present operative morbidity and long-term thyroid function after thyrotoxicosis surgery.
  • To correlate factors influencing long-term thyroid function with outcomes.

Main Methods:

  • Reviewed clinical records of 289 patients undergoing surgery for thyrotoxicosis.
  • Analyzed indications, intraoperative findings, complications, and endocrine status at 1, 2, and 5 years post-surgery.
  • Correlated patient factors (age, sex, treatment duration, thyroid weight, antibody status) with 5-year outcomes.

Related Experiment Videos

Main Results:

  • Low incidence of permanent recurrent laryngeal nerve injury (0.7%) and hypocalcemia (1.7%).
  • Cumulative rates of hypothyroidism and hyperthyroidism at 5 years were 15.6% and 8.0%, respectively.
  • No significant correlation found between analyzed prognostic variables and 5-year outcomes.

Conclusions:

  • Hypothyroidism after surgery for thyrotoxicosis appears early.
  • Recurrent hyperthyroidism rates increase with follow-up duration.
  • Subtotal thyroidectomy necessitates long-term patient monitoring due to unpredictable postoperative endocrine function.