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Updated: Aug 25, 2026

A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease
Published on: March 1, 2022
Risk factors for recurrence of stenosis in Crohn's disease
Marco Scarpa1, Imerio Angriman, Michela Barollo
1Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, University of Padova, Italy. marcoscarpa73@yahoo.it
Abstract:
A major problem in Crohn's disease (CD) surgery is the high frequency of recurrence after bowel resection. Several factors are thought to influence this phenomenon. CD "phenotype" was identified as one of this factors and obstructing CD seems to be a low risk. We analysed the reoperation rate in patients operated for obstructing CD to identify risk factors for postoperative recurrence avoiding any bias due to an high risk phenotype. We reviewed the records of 120 patients treated for stenosing CD and survival analysis was performed using Kaplan-Meier method. Younger age, acute obstruction, emergency conditions, postoperative complications, small bowel disease, ileo-ileal anastomosis and type of suture resulted to be risk factors for CD recurrence.
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