Related Experiment Video
Updated: Aug 25, 2026
Measuring Psoriasis Severity at Home
Published on: March 1, 2024
HLA-B57 is significantly associated with psoriasis in Northeast Romania [corrected]
Venera Vasilca1, A Vasilca, Dorina Munteanu
1Gr. T. Popa University of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Iaşi, Romania.
Unlabelled:
The aim of the study was to identify HLA class I types associated with susceptibility to psoriasis among population of Northeast region of Romania.
Patients And Methods:
27 psoriatic patients and 89 controls were typed serologically for HLA-A and HLA-B lymphocyte expression using CDC-NIH (complement dependent-cytotoxicity--National Institute of Health) method. The Terasaki plates used for HLA class I typing were prepared in our laboratory using antisera of known specificities.
Results And Conclusions:
psoriatic patients in the group of study frequently express HLA-B57 phenotype. The relative risk induced by this phenotype was highly statistically significant (p = 0.0016) while HLA-B13 was not associated with a significant risk for developing psoriasis in patients under study compared with controls (p = 0.48). Also, HLA-B27 (p = 0.96) and HLA-B44 (p = 0.99), reported by others to be associated with late psoriasis, do not meet (a particular) disease susceptibility between psoriatic patients under investigation.
