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Updated: Aug 25, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Community-based study of atrial fibrillation and stroke prevention
1Dept Medical Gerontology, Trinity Centre for Health Sciences, Adelaide and Meath Hospital, Dublin.
Insights
Many atrial fibrillation patients in Ireland are not receiving recommended stroke prevention treatments like anticoagulation or aspirin. This audit highlights a significant gap in care, representing a missed opportunity to prevent strokes in this vulnerable population.
Area of Science:
- Cardiology
- Public Health
- Pharmacology
Background:
- Established benefits of anticoagulation and antiplatelet agents for stroke prevention in atrial fibrillation (AF).
- Limited data exists on stroke prevention strategies in Irish patients with AF.
- Chronic AF management requires effective stroke risk reduction.
Purpose of the Study:
- To assess the adequacy of stroke prevention measures, specifically anticoagulation and aspirin use.
- To evaluate prescribing patterns for stroke prophylaxis in community-dwelling AF patients in Ireland.
- To identify gaps in the implementation of evidence-based stroke prevention in AF.
Main Methods:
- Audit of general medical services (GMS) patients diagnosed with atrial fibrillation.
- Data collection from two general practices in Dublin, Ireland.
- Analysis of anticoagulation status and aspirin use against established contraindications.
Main Results:
- 70 patients with AF identified from 2684 GMS patients.
- 26 patients had contraindications to anticoagulation.
- 47% of patients indicated for warfarin were not anticoagulated (21/44).
- Over half of eligible patients not on anticoagulation were also not on aspirin (20/42).
Conclusions:
- A significant proportion of AF patients eligible for anticoagulation were undertreated.
- Aspirin use was suboptimal in patients where anticoagulation was contraindicated.
- There is a substantial unmet need for improved stroke prevention strategies in Irish AF patients.
Abstract:
The benefits of anticoagulation and antiplatelet agents for stroke prevention in atrial fibrillation (AF) have been established. There is little data on the use of this form of stroke prevention in patients with AF in Ireland. To determine whether adequate stroke prevention measures are taken regarding anticoagulation and aspirin use for patients in the community with chronic AF. Audit of general medical services (GMS) patients with atrial fibrillation in two Dublin general practices. A total of 70 patients with AF were identified from 2684 GMS patients in the two practices: contraindications to anticoagulation were established in 26 of these. In those for whom warfarin was indicated, 21 of 44 (47%) were not anticoagulated. In those not anticoagulated and where aspirin was not contra-indicated, 20 of 42 were not on aspirin. Our study found that almost one third of patients with AF could be anticoagulated but were not, and the alternative of aspirin was only used in just over one half of patients. This represents a lost opportunity for stroke prevention. Various approaches should be explored to remedy this.
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