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Updated: Aug 25, 2026

Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake
Published on: September 21, 2017
Flow injection with inhibited chemiluminescence method for the determination of dopamine hydrochloride
Shuhao Wang1, Lingyun Du, Liangyu Wang
1College of Environmental Science and Engineering, Donghua University, Shanghai 200051, PR China. shuhaowang@sohu.com
Abstract:
A simple rapid and accurate flow injection inhibitory chemiluminescence method has been developed for the determination of dopamine hydrochloride based on its inhibition of the chemiluminescence from the luminol-potassium hexacyanoferrate(III) system. The linear range of determination is 4.0 x 10(-9) - 4.0 x 10(-7) g ml(-1) for dopamine hydrochloride and the detection limit is 1.14 x 10(-9) g ml(-1). The method has been applied to determine the content of dopamine in pharmaceutical preparation with satisfactory results.
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