Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Vaccinations

Vaccinations

Methods of reducing fever

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:

Types of Fever

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:

Patterns of Fever

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.

Yellow Fever

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...

Respiratory Syncytial Virus Disease

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Heart failure hospitalization in patients with and without type 2 diabetes: A population-based retrospective cohort study.

PloS one·2026

Same author

HFpEF risk assessment using H<sub>2</sub>FPEF score in community-dwelling young Hispanic adults.

Frontiers in cardiovascular medicine·2026

Same author

Associations Between Metabolic Dysregulation and Stage B Heart Failure in Hispanic Populations.

Echocardiography (Mount Kisco, N.Y.)·2026

Same author

Integrated Genomic and Transcriptomic Study Reveals <i>MAPK11</i> and <i>PER1</i> as Important Obesity Susceptibility Genes in a High-Risk Hispanic/Latino Population.

Circulation. Genomic and precision medicine·2026

Same author

Local ancestry modulates gene expression: shifting our understanding of genetic regulation and disease association within and across populations.

medRxiv : the preprint server for health sciences·2026

Same author

Gene-by-Sleep Duration Interaction for Glycemic Traits in over 480,000 Individuals.

medRxiv : the preprint server for health sciences·2026

Same journal

Projected health and economic impact of PCV20 vaccination in UK children: a dynamic transmission model.

Expert review of vaccines·2026

Same journal

Evaluating the societal value of adult respiratory vaccination in Sweden: a benefit-cost analysis.

Expert review of vaccines·2026

Same journal

Evaluating the socioeconomic value of adult respiratory immunization in Spain: a benefit-cost analysis.

Expert review of vaccines·2026

Same journal

Whole cell and acellular pertussis vaccines - rethinking the evidence.

Expert review of vaccines·2026

Same journal

Modeling the potential public health and economic impact and cost-effectiveness of vaccination strategies using an adapted COVID-19 vaccine in the Dominican Republic.

Expert review of vaccines·2026

Same journal

Narrative shielding and prebunking: a synergistic strategy against vaccine hesitancy in pediatrics.

Expert review of vaccines·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 8, 2026

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins

Published on: July 1, 2011

Lassa fever vaccine.

Susan P Fisher-Hoch¹, Joseph B McCormick

¹University of Texas Houston Health Science Center, School of Public Health, Brownsville Regional Campus, 80 Fort Brown, Brownsville, Texas 78520, USA. sfisherhoch@utb.edu

Expert Review of Vaccines

|April 2, 2004

Summary

This summary is machine-generated.

Developing a Lassa fever vaccine is crucial for West Africa. Overcoming scientific, political, and economic hurdles is key to creating a safe and effective vaccine for Lassa virus control.

More Related Videos

Measuring Influenza Neuraminidase Inhibition Antibody Titers by Enzyme-linked Lectin Assay

Measuring Influenza Neuraminidase Inhibition Antibody Titers by Enzyme-linked Lectin Assay

Published on: September 6, 2016

Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children

Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children

Published on: February 10, 2023

Related Experiment Videos

Last Updated: Jun 8, 2026

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins

Published on: July 1, 2011

Measuring Influenza Neuraminidase Inhibition Antibody Titers by Enzyme-linked Lectin Assay

Measuring Influenza Neuraminidase Inhibition Antibody Titers by Enzyme-linked Lectin Assay

Published on: September 6, 2016

Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children

Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children

Published on: February 10, 2023

Area of Science:

Virology
Immunology
Public Health

Background:

Lassa fever poses a significant public health threat in West Africa, affecting local populations and healthcare providers.
The rodent host's ecology and endemic conditions necessitate vaccine development for effective control.

Purpose of the Study:

To address the scientific, political, and economic challenges in developing a human Lassa fever vaccine.
To explore optimal vaccine strategies, including antigen choice, vector systems, and delivery formats.

Main Methods:

Investigating the protective role and duration of G-protein immunity.
Evaluating the potential benefits and risks of including N-protein in vaccine formulations.
Considering alternative vaccine vectors (e.g., chimeras, DNA delivery) and formats (live-attenuated vs. killed vaccines).

Main Results:

The duration of G-protein-induced protection is not fully understood.
The potential for N-protein to enhance infection requires further investigation.
Live-attenuated vaccines offer single-shot advantages, while killed vaccines provide better stability for tropical distribution.

Conclusions:

A live-attenuated Lassa vaccine, potentially combined with yellow fever vaccine, is a promising strategy for endemic areas.
Increased funding and new technologies offer hope for clinical trials, but challenges in trial conduct and political stability persist.