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Updated: Jul 13, 2026

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
Beyond perfusion: cerebral vascular reactivity and assessment of microvascular permeability
Andrea Kassner1, Timothy P L Roberts
1Department of Medical Imaging, University Health Network & University of Toronto, Ontario, Canada. andrea.kassner@utoronto.ca
Abstract:
Beyond perfusion, several other related methods are under development for a more complete characterization of different aspects of vascular function. This article will be divided into two parts focusing on two emerging imaging-based assays of vascular status: 1) the cerebrovascular reactivity to a vasodilatory stimulus and 2) the microvascular permeability to a blood-borne MR-visible tracer. Taken together, these approaches can be seen to extend our interrogation of vascular functional and structural integrity and to offer promising clinical and experimental applications.
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