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Eosinophilic meningitis due to Angiostrongylus cantonensis in Switzerland
E Bärtschi1, G Bordmann, J Blum
1Division of Medicine, University Hospital, CH-4101, Bruderholz, Switzerland.
Abstract:
Eosinophilic meningitis is a well-known disease in areas where the rat lung worm Angiostrongylus cantonensis is endemic, i.e. in Southeast Asia and in the Caribbean. We report a case of eosinophilic meningitis due to infection with Angiostrongylus cantonensis in a traveler returning from Cuba. The diagnosis was based upon symptoms of chronic meningitis associated with hyperesthesia and presence of eosinophilia in the cerebrospinal fluid. With increasing mobility rare infections like eosinophilic meningitis due to A. cantonensis may be encountered in the western hemisphere. A Giemsa stain of the cerebrospinal fluid is crucial for a prompt diagnosis that is confirmed by detection of specific antibodies.
Insights
Eosinophilic meningitis caused by the rat lung worm Angiostrongylus cantonensis can occur in travelers. Prompt diagnosis involves cerebrospinal fluid analysis and antibody detection.
Area of Science:
- Neurology
- Infectious Diseases
- Parasitology
Background:
- Eosinophilic meningitis is endemic in regions with Angiostrongylus cantonensis, such as Southeast Asia and the Caribbean.
- Increasing global travel facilitates the spread of rare infections to non-endemic areas.
Observation:
- A case of eosinophilic meningitis in a traveler returning from Cuba is presented.
- Clinical presentation included chronic meningitis symptoms and hyperesthesia.
- Cerebrospinal fluid analysis revealed eosinophilia.
Findings:
- Diagnosis was confirmed by identifying eosinophils in cerebrospinal fluid.
- Specific antibody detection further validated the Angiostrongylus cantonensis infection.
Implications:
- This case highlights the potential for encountering eosinophilic meningitis due to Angiostrongylus cantonensis in the Western Hemisphere.
- Early diagnosis, aided by Giemsa staining of cerebrospinal fluid, is critical.
- Increased awareness and diagnostic vigilance are necessary for rare parasitic infections in travelers.
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