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Treatment of persistent epithelial defects in neurotrophic keratitis with epidermal growth factor: a preliminary open
S Daniele1, J P Gilbard, C L Schepens
1Institute of Ophthalmology, School of Medicine, University of Perugia, Italy.
Abstract:
We report three patients with persistent epithelial defects in the context of neurotrophic keratopathy that healed while on treatment with topically applied, mouse-derived epidermal growth factor (m-EGF). The clinical course of these patients was striking and suggests that EGF may have a potential role in the treatment of persistent epithelial defects in subjects suffering from neurotrophic keratitis.