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Atypical endoscopic features of rectal carcinoids
K-N Shim1, S-K Yang, S-J Myung
1Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Endoscopy
|April 2, 2004
Summary
Atypical endoscopic findings in rectal carcinoid tumors are more common with larger tumor sizes. Ulceration in rectal carcinoids may indicate a worse prognosis.
Area of Science:
- Gastroenterology
- Endocrinology
- Oncology
Background:
- Rectal carcinoid tumors (well-differentiated endocrine neoplasms) typically present with characteristic endoscopic features.
- Atypical endoscopic presentations of rectal carcinoids are not well-documented.
Purpose of the Study:
- To analyze the atypical endoscopic findings in rectal carcinoid tumors.
- To determine the relationship between tumor size and atypical endoscopic features.
- To investigate the prognostic value of ulceration in rectal carcinoids.
Main Methods:
- Retrospective analysis of endoscopic findings in 67 consecutive patients with rectal carcinoids.
- Correlation of tumor size with the presence of atypical endoscopic features.
- Assessment of the association between ulceration and tumor invasion or metastasis.
Main Results:
- Tumor size ranged from 2 mm to 30 mm (average 7.4 mm).
- Atypical endoscopic findings were observed in 22% of patients, increasing significantly with tumor size (P < 0.001).
- Ulceration was present in 4 patients, and 3 of these had invasion or metastasis, compared to only 1 of 63 without ulceration (P < 0.001).
Conclusions:
- Atypical endoscopic appearances of rectal carcinoids are more frequent in larger tumors.
- Ulceration in rectal carcinoids may serve as a prognostic indicator for advanced disease.