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Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
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Published on: June 8, 2022

Balloon pulmonary valvotomy performed in the first year of life

Cláudia Moura1, Ana Carriço, M João Baptista

  • 1Serviço de Cardiologia Pediátrica e Laboratório de Hemodinâmica, Hospital de São João, Porto, Portugal. claudiammoura@yahoo.com

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
|April 3, 2004
PubMed

Insights

Percutaneous pulmonary valvotomy effectively treats right ventricular outflow tract obstruction in infants. This balloon catheter procedure demonstrated a 78% success rate in relieving pulmonary stenosis in the first year of life.

Area of Science:

  • Pediatric Cardiology
  • Interventional Cardiology
  • Congenital Heart Disease

Background:

  • Pulmonary stenosis is a significant congenital heart defect causing right ventricular outflow tract obstruction.
  • Early intervention is crucial for managing pulmonary stenosis in infants to prevent long-term complications.

Purpose of the Study:

  • To evaluate the effectiveness and outcomes of percutaneous pulmonary valvotomy (PPV) using a balloon catheter in infants.
  • To assess the impact of PPV on pressure gradients and patient status within the first year of life.

Main Methods:

  • Retrospective analysis of 27 patients with pulmonary stenosis undergoing balloon valvotomy within the first 12 months of life.
  • Data collected included patient demographics, clinical presentation, echocardiographic findings, procedural details, complications, and follow-up.
  • Statistical analysis involved median values and the Wilcoxon test for pressure gradients, with mean and standard deviation for other variables.

Main Results:

  • The procedure was performed in 23 patients, with a median age of 60 days; 43.5% were treated within the first 28 days of life.
  • A significant reduction in the right ventricular peak systolic pressure gradient was observed (115 mmHg to 48 mmHg, p < 0.001).
  • The success rate was 78% (21 of 27 patients), with a mean follow-up of 40.1 months. 13% had a gradient >40 mmHg post-procedure.

Conclusions:

  • Percutaneous pulmonary valvotomy is an effective treatment for relieving right ventricular outflow tract obstruction in infants with pulmonary stenosis.
  • Early balloon valvotomy in the first year of life offers a high success rate and favorable outcomes for managing this condition.
Abstract

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