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[Gallbladder motor activity in patients with virus hepatitis B]
Arkadiusz Mamos1, Paweł Wichan, Jan Chojnacki
1Klinika Gastrologii IMW, Uniwersytet Medyczny w Łodzi.
Summary
Patients with acute virus hepatitis B exhibit gallbladder hyperreactivity, with decreased gallbladder volume and increased ejection fraction. These motor activity disorders persist even after two months of observation.
Area of Science:
- Hepatology
- Gastroenterology
- Medical Imaging
Background:
- Acute virus hepatitis B often presents with dyspeptic discomfort, potentially linked to gastrointestinal motility disorders.
- Gallbladder dysfunction may contribute to these symptoms, supported by ultrasonographic findings of gallbladder wall thickening in early-stage hepatitis B.
Purpose of the Study:
- To investigate gallbladder motor activity in patients during the acute phase of virus hepatitis B.
- To assess changes in gallbladder function over a two-month observation period.
Main Methods:
- A group of 15 acute virus hepatitis B patients underwent serial ultrasonographic examinations of gallbladder motor activity.
- Measurements included total gallbladder volume, ejection fraction, and volume response to a test meal, compared with 25 healthy controls.
Main Results:
- Patients with acute virus hepatitis B showed significantly reduced gallbladder volume and increased ejection fraction compared to controls.
- These gallbladder hyperreactivity patterns persisted, although showing some decrease, even at 8 weeks post-diagnosis.
Conclusions:
- Acute virus hepatitis B is associated with gallbladder hyperreactivity, contributing to dyspeptic symptoms.
- Gallbladder motor function abnormalities may be a prolonged complication of hepatitis B, requiring further investigation.