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Updated: Aug 4, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
14:19

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction

Published on: June 29, 2013

Fetal growth restriction due to placental disease

Ahmet A Baschat1, Kurt Hecher

  • 1Department of Obstetrics, Gynecology & Reproductive Sciences, Center for Advanced Fetal Care, University of Maryland, Baltimore 21201, USA.

Seminars in Perinatology
|April 3, 2004
PubMed

Insights

Intrauterine growth restriction (IUGR) poses risks to newborns, often stemming from placental issues. Comprehensive fetal evaluation and timely delivery are crucial for managing IUGR effectively.

Area of Science:

  • Obstetrics and Gynecology
  • Fetal Medicine
  • Perinatology

Background:

  • Normal fetal growth is influenced by genetics and maternal/fetal health.
  • Intrauterine growth restriction (IUGR) increases risks for perinatal and long-term outcomes.
  • Placental disease is a primary clinical cause of IUGR.

Purpose of the Study:

  • To review fetal responses to placental insufficiency.
  • To discuss antenatal management protocols for IUGR.
  • To highlight the importance of timely delivery in IUGR cases.

Main Methods:

  • Concurrent evaluation of fetal biometry, amniotic fluid volume, and heart rate patterns.
  • Utilizing arterial and venous Doppler studies.
  • Incorporating biophysical variables and gestational age assessment.

Main Results:

  • Fetal cardiovascular and behavioral responses are linked to placental insufficiency and metabolic status.
  • Comprehensive evaluation using multiple parameters provides a thorough assessment of IUGR.
  • Timing of delivery is critical in antenatal management when intrauterine therapy is not successful.

Conclusions:

  • Placental insufficiency significantly impacts fetal well-being and growth.
  • A multi-parameter approach is essential for evaluating fetuses with IUGR.
  • Optimizing delivery timing is paramount for improving outcomes in IUGR pregnancies.

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