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Updated: May 1, 2026
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A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood
Published on: April 28, 2016
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[Correlation between plasma leptin level and premature infant weight loss]
Zhuang-gui Chen1, Xue-hua Zhang, Zheng-xian He
1Department of Pediatrics, The Third Affiliated Hospital, Sun Yet-sen University, Guangzhou 510630, China.
Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics
|April 3, 2004
Summary
Plasma leptin levels positively correlate with weight loss in premature infants. This suggests leptin plays a role in regulating energy balance and body weight during early neonatal development.
Area of Science:
- Neonatology
- Endocrinology
- Pediatrics
Context:
- Leptin, a hormone from fat cells, influences body weight and energy balance.
- Its precise role in human neonates, especially premature infants, remains under investigation.
- Premature infants experience significant weight loss and energy balance challenges post-birth.
Purpose:
- To investigate the relationship between plasma leptin levels and weight loss in premature infants.
- To explore the role of leptin in energy balance and body weight regulation during the neonatal period for premature infants.
Summary:
- This study measured plasma leptin concentrations in 26 premature infants using radioimmunoassay.
- Results showed a significant positive correlation between plasma leptin levels and the degree of body weight loss.
- Leptin levels also correlated positively with body length and Kaup index, but less so with head circumference over time.
Impact:
- Findings suggest leptin is involved in the energy balance and body weight regulation of premature infants.
- Leptin may play a crucial role in the growth and development of these vulnerable infants.
- This research highlights a potential biomarker for monitoring neonatal well-being and development.
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