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In vivo sister chromatid differentiation and baseline sister chromatid exchanges in a mouse ascites tumour model
A Chakrabarti1, S Acharya, A K Pal
1Department of Zoology, Vivekananda College, Burdwan, India.
Indian Journal of Experimental Biology
|January 1, 1992
Abstract:
Induction of differentially stained sister chromatids at G2/M and determination of baseline sister chromatid exchanges (SCEs) in ascites form of mouse sarcoma 180 cell line have been done by in vivo incorporation of 5-bromodeoxyuridine (BrdU) for two consecutive DNA replication cycles. The baseline SCE frequency is 6.24 at log phase of tumour growth.