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Splenic abscess in southern Taiwan.

Chen-Hsiang Lee1, Hsieh-Shong Leu, Tsung-Hui Hu

  • 1Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan, ROC.

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
|April 3, 2004
PubMed
Summary

Splenic abscess is rare but serious, often presenting with fever and left upper quadrant pain. Klebsiella pneumoniae is the most common pathogen, highlighting the need for further research in immunocompromised patients.

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Area of Science:

  • Infectious Diseases
  • Clinical Microbiology
  • Abdominal Surgery

Background:

  • Splenic abscess is a rare but potentially life-threatening condition.
  • Increasing prevalence of immunocompromised individuals contributes to a higher risk.
  • Understanding clinical features and causative pathogens is crucial for effective management.

Purpose of the Study:

  • To retrospectively analyze the clinical characteristics of splenic abscess.
  • To identify the spectrum of pathogens isolated from splenic abscess cases.
  • To provide insights into the management of splenic abscess.

Main Methods:

  • Retrospective analysis of 49 splenic abscess cases treated between 1981 and 2001.
  • Review of patient demographics, clinical presentations, laboratory findings, and microbiological data.

Related Experiment Videos

  • Identification of isolated pathogens and their antimicrobial susceptibility.

    • Main Results:

    • Fever, left upper quadrant abdominal pain, left pleural effusion, and splenomegaly were the most common presentations.
    • Klebsiella pneumoniae was the predominant pathogen, followed by Escherichia coli and Salmonella spp.
    • Multiple splenic abscesses were more frequent in patients with underlying malignancies.

    Conclusions:

    • Splenic abscess requires prompt diagnosis and treatment, with a high index of suspicion in febrile patients with abdominal pain.
    • Klebsiella pneumoniae is a significant causative agent, particularly in the Taiwanese population.
    • Multicenter studies are essential to elucidate epidemiological features and optimize therapeutic strategies for splenic abscess, especially in immunocompromised hosts.