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Electric Cell-substrate Impedance Sensing for the Quantification of Endothelial Proliferation, Barrier Function, and Motility
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Electrical impedance measurements: an objective measure of prelabor cervical change

M P O'Connell1, N J Avis, B H Brown

  • 1Coombe Women's Hospital, Dublin, Republic of Ireland.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|April 6, 2004
PubMed

Objective:

To investigate the use of electrical impedance measurements of the pregnant cervix as an objective measure of cervical favorability (Bishop score > or = 5).

Methods:

A prospective study of 86 women, investigating electrical impedance measurements of the pregnant cervix at the time of induction of labor. Transfer electrical impedance measurements were made by placing a tetrapolar pencil probe of 8 mm in diameter on the surface of the cervix. A Bishop score was determined simultaneously.

Results:

A mean resistivity (standard error of the mean) of 7.03 (6.01-8.04) omega(m) was measured for the unfavorable group and 5.34 (4.61-6.07) omega(m) for the favorable group. This was a statistically significant difference (p = 0.016).

Conclusion:

We highlight the ability of this safe, painless technique to differentiate the favorable from the unfavorable cervix at induction of labor.

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Voltage and current measurements using a standard voltmeter and ammeter alter the circuit being measured either by drawing or resisting the current flow, which introduces uncertainties in the measurements. Null measurements balance the voltages so that no current flows through the measuring device and, therefore, no alterations occur in the measured circuit.
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