Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analytical goals for coagulation tests based on biological variation.

Yui Wada1, Masako Kurihara, Mitsuko Toyofuku

  • 1Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Hospital, Fukuoka, Japan.

Clinical Chemistry and Laboratory Medicine
|April 6, 2004
PubMed
Summary

This study determined biological variation for 13 coagulation tests in healthy adults. The findings establish achievable precision and bias limits for clinical laboratory quality control.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The primed Stroop is not a Stroop task: Evidence from delta plots.

Memory & cognition·2026
Same author

Meaning composition in the processing of transposed-constituent compound nonwords.

Journal of experimental psychology. Human perception and performance·2025
Same author

Priming the distractor can eliminate the Stroop interference effect.

Psychonomic bulletin & review·2024
Same author

Taboo language across the globe: A multi-lab study.

Behavior research methods·2024
Same author

Mirror letter priming is rightward-biased but not inhibitory: Little evidence for a mirror suppression mechanism in the recognition of mirror letters.

Journal of experimental psychology. Learning, memory, and cognition·2023
Same author

Diacritic priming in novice readers of diacritics.

Journal of experimental psychology. Human perception and performance·2023

Area of Science:

  • Clinical Laboratory Science
  • Hematology
  • Biostatistics

Background:

  • Establishing reference limits for laboratory data relies on biological variation.
  • Limited data exists on biological variation in coagulation testing compared to clinical chemistry.

Purpose of the Study:

  • To calculate the biological variation of 13 coagulation tests.
  • To determine allowable imprecision and bias limits for these tests at Kyushu University Hospital.

Main Methods:

  • 17 healthy individuals (balanced gender and age distribution) participated.
  • Monthly blood samples were collected over 12 months (June 2001-May 2002).
  • Biological variation and allowable limits for imprecision and bias were calculated.

Main Results:

Related Experiment Videos

  • Biological variation was calculated for 13 key coagulation tests.
  • Allowable imprecision and bias limits were established based on these variations.
  • Calculated limits are considered attainable within routine laboratory settings.

Conclusions:

  • The study provides essential biological variation data for coagulation tests.
  • Established limits support enhanced quality control in clinical coagulation testing.
  • Findings indicate that current laboratory precision is adequate for these tests.