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[Multiple meningiomas: report of 32 cases]
Liang-wen Zhang1, Shu-gan Zhu, Cheng-yuan Wu
1Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250012, China.
Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|April 6, 2004
Summary
Multiple meningiomas, tumors in the brain lining, likely arise from varied origins, with estrogen potentially playing a role. Surgical removal of all tumors is feasible and recommended for better outcomes.
Area of Science:
- Neuro-oncology
- Pathology
- Genetics
Context:
- Multiple meningiomas are rare intracranial neoplasms.
- Understanding their diverse origins and optimal management is crucial.
Purpose:
- To investigate the genesis, classification, diagnosis, and treatment of multiple meningiomas.
- To analyze treatment outcomes based on tumor classification.
Summary:
- A retrospective study of 32 multiple meningioma cases was conducted, classifying them into five groups: primary, postoperative, neurofibromatosis-associated, meningiomatosis, and those with other intracranial tumors.
- All patients underwent surgical resection, with 25 achieving a cure and 7 showing improvement.
- Findings suggest varied cytogenesis and a potential role for estrogen in multiple meningioma development.
Impact:
- This study advocates for single-stage resection of all tumors when feasible, acknowledging the tolerance for staged operations.
- It highlights that treatment principles and prognosis differ across various multiple meningioma classifications.