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[Multiple meningiomas: report of 32 cases]

Liang-wen Zhang1, Shu-gan Zhu, Cheng-yuan Wu

  • 1Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250012, China.

Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|April 6, 2004
PubMed
Abstract

Insights

Multiple meningiomas, tumors in the brain lining, likely arise from varied origins, with estrogen potentially playing a role. Surgical removal of all tumors is feasible and recommended for better outcomes.

Area of Science:

  • Neuro-oncology
  • Pathology
  • Genetics

Context:

  • Multiple meningiomas are rare intracranial neoplasms.
  • Understanding their diverse origins and optimal management is crucial.

Purpose:

  • To investigate the genesis, classification, diagnosis, and treatment of multiple meningiomas.
  • To analyze treatment outcomes based on tumor classification.

Summary:

  • A retrospective study of 32 multiple meningioma cases was conducted, classifying them into five groups: primary, postoperative, neurofibromatosis-associated, meningiomatosis, and those with other intracranial tumors.
  • All patients underwent surgical resection, with 25 achieving a cure and 7 showing improvement.
  • Findings suggest varied cytogenesis and a potential role for estrogen in multiple meningioma development.

Impact:

  • This study advocates for single-stage resection of all tumors when feasible, acknowledging the tolerance for staged operations.
  • It highlights that treatment principles and prognosis differ across various multiple meningioma classifications.

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