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Updated: Aug 25, 2026

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells
Published on: May 19, 2023
The immune response to bovine viral diarrhea virus: a constantly changing picture
Christopher C L Chase1, Gamal Elmowalid, Ausama A A Yousif
1Department of Veterinary Science, South Dakota State University, P.O. Box 2175, Brookings, SD 57007, USA. christopher_chase@sdstate.edu
Abstract:
Bovine viral diarrhea virus (BVDV) is one of the major immuno-suppressive viruses of cattle. The effect on the innate and acquired immune system is unique and results in dramatic immune dysfunction. BVDV infection also has the ability to cause persistent infection (PI) in the developing fetus. This Pl syndrome creates a requirement for high levels of BVDV immunity from vaccines to prevent these infections. BVDV vaccines and their future development continue to be an enigma in the control of BVDV.
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