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Updated: Aug 25, 2026

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
Modern hepatic imaging
Larissa Braga1, Ulrich Guller, Richard C Semelka
1Department of Radiology, University of North Carolina at Chapel Hill, 10 Manning Drive, CB# 7510, Chapel Hill, NC 27599-7510, USA.
Abstract:
This article provides a brief overview of the current status of commonly employed diagnostic techniques--US, CT, MR, and PET--for the evaluation of liver metastases and HCC as well as a description of imaging in RF ablation and liver transplantation. The various advantages and limitations of the techniques have been outlined. At the present time, at our center, MRI is used most often to evaluate these liver pathologies, due to its high accuracy for lesion detection and characterization.
Insights
This review covers diagnostic imaging techniques like ultrasound (US), CT, MRI, and PET for liver metastases and hepatocellular carcinoma (HCC). MRI is preferred for its high accuracy in detecting and characterizing liver lesions.
Area of Science:
- Radiology
- Medical Imaging
- Hepatobiliary Diseases
Background:
- Accurate diagnosis of liver metastases and hepatocellular carcinoma (HCC) is crucial for patient management.
- Various imaging modalities are employed, each with specific strengths and weaknesses.
Purpose of the Study:
- To provide an overview of current diagnostic imaging techniques for liver metastases and HCC.
- To describe imaging in radiofrequency (RF) ablation and liver transplantation.
- To outline the advantages and limitations of each technique.
Main Methods:
- Review of commonly used diagnostic imaging techniques: ultrasonography (US), computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET).
- Discussion of imaging applications in radiofrequency ablation and liver transplantation.
- Comparative analysis of the advantages and limitations of each modality.
Main Results:
- Ultrasound (US), CT, MRI, and PET are established methods for evaluating liver metastases and HCC.
- MRI demonstrates high accuracy in lesion detection and characterization, making it a preferred choice at the author's center.
- Imaging plays a vital role in monitoring RF ablation and assessing outcomes after liver transplantation.
Conclusions:
- The selection of imaging technique depends on the specific clinical scenario and the information required.
- MRI offers superior accuracy for detecting and characterizing liver lesions, guiding treatment decisions.
- Continued advancements in imaging technology enhance the evaluation and management of liver pathologies.
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