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Updated: Aug 25, 2026

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Published on: May 2, 2025
Reversal of protein-losing enteropathy with calcium replacement in a patient after Fontan operation
Soo-Jin Kim1, In-Seung Park, Jin-Young Song
1Department of Pediatric Cardiology, Sejong Heart Institute, Sosa-Ku Pucheon City, Kyunggi-do, Korea. ksoojn@yahoo.co.kr
Abstract:
Protein-losing enteropathy occurs in patients following the modified Fontan procedure. Treatment is still controversial. We describe a boy who developed protein-losing enteropathy 18-months after an extracardiac Fontan procedure. Treatment with calcium for hypocalcemia attenuated the protein loss with subsequent normalization of serum total protein and albumin levels. Decrease of oral calcium and subsequent decrease of serum ionized calcium level were associated with relapse of hypoalbuminemia. This was again treated successfully with calcium and vitamin D replacement.
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