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Published on: May 25, 2017
Lumbar disk herniation: correlation of histologic findings with marrow signal intensity changes in vertebral
Gebhard Schmid1, Andreas Witteler, Roland Willburger
1Department of Radiology and Nuclear Medicine, St Josef Hospital, Ruhr-Universität Bochum, Gudrunstrasse 56, 44791 Bochum, Germany. gebhard.schmid@ruhr-uni-bochum.de
Purpose:
To compare findings at preoperative magnetic resonance (MR) imaging with data for tissue composition of herniated disks in patients after microsurgical removal of herniated material.
Materials And Methods:
Fifty-one patients underwent MR imaging before microsurgical removal of extruded lumbar disk herniation material. Marrow signal intensity changes along the cartilaginous endplates were classified according to Modic types 1-3. Severity of changes was evaluated with respect to extension along the endplate in the anteroposterior diameter (0%, <33%, 33%-66%, >66%). The existence of a dorsal vertebral corner defect was evaluated in relation to the existence of hyaline cartilage in the disk extrusion material.
Results:
Mean tissue composition of herniated material in all patients was 63% anulus fibrosus, 30% nucleus pulposus, and 8% cartilaginous endplate. Twenty-five of the 51 patients had hyaline cartilaginous material in the extrusion (range, 5%-50%). Patients without marrow signal intensity changes along the cartilaginous endplate showed significantly less cartilaginous material in the extruded disk (P =.023, Fisher exact test). Mean percentage hyaline cartilage in patients without changes was 2% +/- 4 (SD) (Modic type 1, 16% +/- 15; type 2, 10% +/- 12). When the changes extended 33% of the vertebral endplate, there was cartilaginous endplate material in the extruded disk (P =.006). Cartilage from the endplate was present in the extruded disk material in 40% (16 of 40) of patients without a vertebral corner defect and in 82% (nine of 11) of patients with a vertebral corner defect (P =.019).
Conclusion:
Avulsion-type disk herniation seems to be common, and vertebral endplate marrow signal intensity changes on MR images are indicative of cartilaginous material in the extruded disk herniation material.
Insights
Magnetic resonance (MR) imaging showing vertebral endplate changes can indicate cartilaginous material in herniated disc material. This finding is common in avulsion-type disc herniations, aiding surgical planning.
Area of Science:
- Orthopedic Surgery
- Radiology
- Spine Surgery
Background:
- Lumbar disc herniation is a common condition requiring surgical intervention.
- Accurate preoperative assessment of herniated disc material composition is crucial for surgical planning and predicting outcomes.
Purpose of the Study:
- To correlate preoperative magnetic resonance (MR) imaging findings with the tissue composition of herniated disc material.
- To investigate the relationship between vertebral endplate changes and the presence of cartilaginous material in extruded disc fragments.
Main Methods:
- Fifty-one patients with lumbar disc herniation underwent preoperative MR imaging.
- Marrow signal intensity changes (Modic types 1-3) and endplate defect severity were assessed.
- Tissue composition of surgically removed herniated material was analyzed.
Main Results:
- Mean herniated material composition was 63% anulus fibrosus, 30% nucleus pulposus, and 8% cartilaginous endplate.
- Patients with vertebral endplate marrow signal intensity changes had significantly more cartilaginous material in their herniated discs (P=.023).
- Vertebral corner defects were associated with a higher prevalence of endplate cartilage in extruded material (82% vs. 40%, P=.019).
Conclusions:
- Vertebral endplate marrow signal intensity changes on MR imaging are indicative of cartilaginous material in herniated disc fragments.
- Avulsion-type disc herniations, characterized by endplate involvement, appear to be common.
- MR imaging findings can help predict the presence of cartilage in herniated disc material, potentially influencing surgical approaches.
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