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[Clinical trials--historical development, regulation and updated data].

Orly Tamir1, Joshua Shemer

  • 1Israeli Center for Technology Assessment in Health Care, Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer.

Harefuah
|April 7, 2004
PubMed
Summary
This summary is machine-generated.

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Clinical trials are essential for medical research, connecting science to patient care. This overview examines their history, regulations, and global trends, focusing on Israel.

Area of Science:

  • Medical research
  • Clinical trials
  • Regulatory affairs

Context:

  • Clinical trials serve as a critical link between medical research and practical healthcare applications.
  • The 20th century saw the establishment of international standards and regulations for ethical clinical trial conduct.
  • Advancements in pharmaceuticals, biologics, and medical devices have driven an increase in global clinical trial activity.

Purpose:

  • To provide a historical overview of clinical trials.
  • To outline the regulatory frameworks governing clinical trials.
  • To present data on the scale and financial aspects of clinical trials, with a specific focus on Israel.

Summary:

  • This paper reviews the historical evolution and regulatory underpinnings of clinical trials.

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  • It details the increasing number and scope of clinical trials globally.
  • Data on the extent and costs of clinical trials are presented, highlighting trends in Israel.

    • Impact:

    • Informs researchers and regulatory bodies about the historical context and evolution of clinical trial standards.
    • Provides insights into the global landscape and economic impact of clinical trials.
    • Offers a focused analysis of clinical trial activities within Israel's research environment.