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Updated: Aug 25, 2026

Isolation and Compositional Analysis of Plant Cuticle Lipid Polyester Monomers
Published on: November 22, 2015
Determination of bisphenol A diglycidyl ether and its hydrolysis and chlorohydroxy derivatives by liquid
Raquel Sendón García1, Perfecto Paseiro Losada
1Analytical Chemistry, Nutrition and Bromatology Department, Pharmacy Faculty, Campus Sur University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Abstract:
European Legislation establishes that the sum of the migration levels of bisphenol A diglycidyl ether (BADGE), its hydrolysis (BADGE.H2O and BADGE.2H2O) and chlorohydroxy (BADGE.HCl, BADGE.2HCl and BADGE.H2O.HCl) derivatives shall not exceed the limit of 1 mg/kg in foodstuffs or food simulants. A reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with mass spectrometry detection using atmospheric pressure chemical ionisation (APCI) is developed for the separation, quantification and identification of the interesting compounds. Quantification of the analytes was carried out in the single ion recording mode, once their characteristic masses were selected from their full spectra, by using an external calibration. The optimised method was suitable for the migration evaluation of these compounds in different samples.
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