Introducing a novel class of four-component reactions
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Updated: Aug 25, 2026

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
Published on: November 9, 2019
Ahmad Shaabani1, Mohammad Bagher Teimouri, Ayoob Bazgir
1Department of Chemistry, Shahid Beheshti University, 1983963113 Tehran, Iran. a-shaabani@cc.sbu.ac.ir
Abstract:
A novel four-component reaction approach to the efficient synthesis of triamide and amidodiester derivatives using amines or alcohols, aldehydes and alkyl or aryl isocyanides in the presence of Meldrum's acid as a CH acid, instead of carboxylic acid of Ugi four-component reaction, was studied.
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