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Updated: Aug 25, 2026

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)
Published on: April 7, 2021
[Analysis of acute respiratory dysfunction as a risk factor of multiple injuries]
Objective:
To study the relationship between multiple injuries and acute respiratory dysfunction (ARD).
Methods:
One hundred and ten patients with multiple injuries admitted during the last 6 years were retrospectively analyzed. With ARD as the dependent variable and other 11 factors as independent variables, all analysis was done statistically on computer to identify the complication of ARD as a risk factor.
Results:
Multivariable and single argument analysis showed systemic inflammatory response syndrome (SIRS), pulmonary contusion, co-existing lung disease as chronic obstructive pulmonary disease (COPD) and pneumonia, moderate hemothorax and pneumothorax, duration of shock over 12 hours, age over 55 years, injury severity score(ISS)>24 were high risk factors.
Conclusion:
Patients with multiple injuries with high risk factors should be kept under closer observation in order to prevent ARD and multiple organ dysfunction syndromes (MODS).
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