Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primer on clinical acid-base problem solving.

William L Whittier1, Gregory W Rutecki

  • 1Department of Internal Medicine, Rush University Medical Center, USA.

Disease-A-Month : DM
|April 8, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"A Change Is Gonna Come" to Treatment of Lupus Nephritis: A Review.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2025
Same author

KDOQI US Commentary on the 2021 KDIGO Clinical Practice Guideline for the Management of Glomerular Diseases.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2023
Same author

The lupus nephritis classification: lost in translation.

Current opinion in nephrology and hypertension·2023
Same author

IgA Nephropathy with Crescents: A Single-Center Experience.

American journal of nephrology·2023
Same author

Percutaneous Renal Biopsy Using an 18-Gauge Automated Needle Is Not Optimal.

American journal of nephrology·2021
Same author

Bisphosphonate Versus Bisphosphonate and Calcitonin for the Treatment of Moderate to Severe Hypercalcemia of Malignancy.

The Annals of pharmacotherapy·2020
Same journal

Disturbances due to cold.

Disease-a-month : DM·2026
Same journal

GLP-1 agonist and neuroprotection in Stroke and Parkinson's disease: A systematic review.

Disease-a-month : DM·2026
Same journal

GLP-1 receptor agonists for weight management and potential thromboembolic risk reduction in high risk population with cancer, diabetes, cardiovascular disease: A systematic review.

Disease-a-month : DM·2026
Same journal

Periodontal disease and diabetic kidney disease: A comprehensive analysis.

Disease-a-month : DM·2026
Same journal

Foreword for Glucagon-like peptide-1 receptor agonists (GLP-1) and its promise for potential benefits.

Disease-a-month : DM·2026
Same journal

Foreword for insulin autoimmune syndrome (Hirata Disease): An updated review of epidemiology, pathophysiology, clinical features, diagnosis, and management.

Disease-a-month : DM·2026
See all related articles

Mastering acid-base problem solving is crucial for diagnosing complex diseases. The

Area of Science:

  • Internal Medicine
  • Nephrology
  • Critical Care Medicine

Background:

  • Acid-base problem solving is essential in modern medicine.
  • Newer diseases like Bartter syndrome, Gitelman syndrome, D-lactic acidosis, and bulimia nervosa have characteristic acid-base findings.
  • Accurate diagnosis relies on a systematic approach to arterial pH, pCO2, bicarbonate, and electrolytes.

Purpose of the Study:

  • To present the 'Rules of Five' as a systematic tool for acid-base problem solving.
  • To demonstrate how this systematic approach aids in diagnosing simple and complex acid-base disorders, including triple disturbances.
  • To highlight the integration of electrolyte abnormalities and urine electrolytes into diagnostic algorithms.

Main Methods:

  • Application of the 'Rules of Five' to analyze acid-base disturbances.

Related Experiment Videos

  • Incorporation of electrolyte abnormalities (e.g., hypokalemia) into diagnostic algorithms.
  • Utilizing urine electrolytes for further characterization of specific acid-base disorders.

    • Main Results:

    • The 'Rules of Five' provide a consistent method for determining the cause of various acid-base disorders.
    • Acid-base patterns act as a common diagnostic pathway across medical subspecialties.
    • The approach facilitates diagnosis in diverse conditions, from infectious diseases to endocrinology and psychiatry.

    Conclusions:

    • Systematic acid-base problem solving, exemplified by the 'Rules of Five,' is key to diagnosing a wide range of contemporary diseases.
    • This approach serves as a unifying diagnostic strategy applicable across all medical disciplines.
    • Effective acid-base assessment unlocks diagnoses for conditions often presenting with complex metabolic disturbances.