Related Experiment Video
Updated: Mar 23, 2026
Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
Cytomegalovirus Retinitis in infancy
S M E Wren1, A R Fielder, D Bethell
1Western Eye Hospital, London, UK.
Purpose:
To describe the presentation of cytomegalovirus retinitis (CMVR) in a series of infants.
Methods:
Immunocompromised infants with either HIV or systemic cytomegalovirus (CMV) were examined for CMVR. Ocular involvement was recorded and monitored by digital imaging.
Results:
Five infants were detected to have CMVR. All the infants demonstrated changes within the macula. One infant progressed from a fine granular pattern to fulminant CMVR.
Conclusion:
Infants under a year with CMVR have a predilection for the disease to present at the macula, in contrast to the presentation in adults, which tends to involve more peripheral parts of the retina.
