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Updated: Aug 24, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Endocarditis with ruptured cerebral aneurysm caused by Cardiobacterium valvarum sp. nov
Xiang Y Han1, Michelle C Meltzer, Joan T Woods
1Section of Clinical Microbiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA . xhan@mdanderson.org
Abstract:
A fastidious gram-negative bacterium was isolated from the blood of a 37-year-old man who had insidious endocarditis with a sudden rupture of a cerebral aneurysm. Characterization of the organism through phylogenetic and phenotypic analyses revealed a novel species of Cardiobacterium, for which the name Cardiobacterium valvarum sp. nov. is proposed. C. valvarum will supplement the current sole species Cardiobacterium hominis, a known cause of endocarditis. Surgeries and antibiotic treatment cured the patient's infection and associated complications. During cardiac surgery, a congenital bicuspid aortic valve was found to be the predisposing factor for his endocarditis.
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