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Published on: February 27, 2017
Infrapopliteal angioplasty
Sachin Rastogi1, S William Stavropoulos
1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Insights
Endovascular therapy, including infrapopliteal percutaneous transluminal angioplasty (PTA), shows promise for limb salvage in chronic critical limb ischemia (CLI). Optimizing patient selection and surveillance can improve outcomes, offering an alternative to bypass surgery.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Interventions
Background:
- Endovascular therapy for infrapopliteal vascular disease is increasingly accepted.
- It is primarily used for limb salvage and wound healing in chronic critical limb ischemia (CLI).
- Its role in treating lifestyle-altering claudication is still debated.
Purpose of the Study:
- To evaluate the safety and effectiveness of endovascular therapy for infrapopliteal vascular disease.
- To assess its role as an alternative to bypass surgery for CLI.
- To identify factors for improving outcomes in infrapopliteal percutaneous transluminal angioplasty (PTA).
Main Methods:
- Review of current evidence on endovascular therapy for infrapopliteal disease.
- Analysis of limb salvage rates and patency following infrapopliteal PTA.
- Discussion of patient selection criteria and surveillance strategies.
Main Results:
- High limb salvage rates are achievable with infrapopliteal PTA for CLI.
- These rates suggest PTA as a viable alternative to bypass surgery.
- Patency can be enhanced through careful patient selection and monitoring.
Conclusions:
- Endovascular therapy, particularly PTA, is effective for limb salvage in CLI.
- Proper patient selection and surveillance are crucial for optimizing outcomes.
- Future advancements may further improve results of tibial artery endovascular interventions.
Abstract:
Endovascular therapy for infrapopliteal vascular disease is gaining acceptance as there is growing evidence demonstrating its safety and effectiveness. It is most commonly used to treat patients with chronic critical limb ischemia (CLI) for limb salvage and wound healing. Its use to treat lifestyle altering claudication remains controversial. For the treatment of CLI, limb salvage rates with infrapopliteal percutaneous transluminal angioplasty (PTA) are high enough that these techniques are offering an alternative to bypass surgery. Current patency rates from infrapopliteal PTA can be improved further by proper patient selection, ensuring straight-line flow to the foot in at least one tibial vessel, and close patient surveillance for early reintervention. Possible future advances including the use of drug-eluting stents, cutting balloons, and aggressive antiplatelet regimens are being tested to improve clinical outcomes following endovascular interventions on the tibial arteries.
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