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Updated: Aug 24, 2026

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
10:02

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

Published on: March 12, 2020

[Therapeutic efficacy of nootropil different doses in attention deficit hyperactivity disorder]

N N Zavadenko, S Iu Suvorinova

    Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
    |April 10, 2004
    PubMed

    Insights

    Nootropil (piracetam) improved behavior, motor skills, and attention in children with Attention Deficit Hyperactivity Disorder (ADHD). Higher doses showed greater therapeutic effects in this open-label study.

    Area of Science:

    • Pediatric Neurology
    • Child Psychology
    • Pharmacology

    Background:

    • Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder in children.
    • ADHD significantly impacts learning, behavior, and social functioning.
    • Effective therapeutic interventions for pediatric ADHD are crucial.

    Purpose of the Study:

    • To evaluate the therapeutic efficacy of nootropil (piracetam) in children diagnosed with ADHD.
    • To compare the effects of two different nootropil dosages on ADHD symptoms.
    • To assess the impact of nootropil on behavioral, motor, and attentional domains.

    Main Methods:

    • An open-label, controlled study involving 80 children (aged 6-11) with ADHD.
    • Participants were divided into three groups: two receiving daily oral nootropil (70 mg/kg or 40 mg/kg) and one control group.
    • Assessments included parent questionnaires, neurological examinations, and psychological testing over one month.

    Main Results:

    • Nootropil therapy demonstrated improvements in behavioral characteristics, motor coordination, and attention (continuous, selective, divided).
    • A 60% response rate was observed in the group receiving 70 mg/kg of nootropil.
    • The group treated with 40 mg/kg nootropil showed a 43% response rate.

    Conclusions:

    • Nootropil (piracetam) shows positive therapeutic effects in managing ADHD symptoms in children.
    • Higher dosages of nootropil (70 mg/kg) appear to yield more significant improvements compared to lower dosages (40 mg/kg).
    • Further research into optimal nootropil dosing for pediatric ADHD is warranted.

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