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Related Experiment Videos

Cognitive performance in patients with COPD.

Jeroen J W Liesker1, Dirkje S Postma, Rypko J Beukema

  • 1Department of Pulmonary Diseases, University Hospital Groningen, Hanzeplein 1, Postbox 30001 NL-9700-RB, Groningen, The Netherlands.

Respiratory Medicine
|April 10, 2004
PubMed
Summary

Cognitive impairments affect even non-hypoxemic patients with Chronic Obstructive Pulmonary Disease (COPD). These deficits in cognitive performance were not linked to reduced quality of life.

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Area of Science:

  • Neurology
  • Pulmonology
  • Psychology

Background:

  • Patients with Chronic Obstructive Pulmonary Disease (COPD) and hypoxemia exhibit cognitive deficits.
  • Cognitive performance in non-hypoxemic COPD patients remains understudied.

Purpose of the Study:

  • To assess cognitive performance in stable, non-hypoxemic COPD patients.

Main Methods:

  • Recruited stable COPD patients (PaO2 > 8.0 kPa) and healthy controls matched for age, IQ, and education.
  • Administered the Stroop Colour Word Test, Trailmaking, Wechsler Adult Intelligence Scale digit-symbol test, Groningen Intelligence Test addition subtest, and Story Recall.

Main Results:

  • COPD patients demonstrated significantly poorer performance on Trailmaking B, digit-symbol, and addition subtests.

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  • No significant correlation was found between cognitive test results and the Chronic Respiratory Questionnaire.

    • Conclusions:

    • Non-hypoxemic COPD patients exhibit significant cognitive impairments.
    • These cognitive deficits are not associated with diminished health-related quality of life.