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Sulfamethoxazole-imprinted polymer for selective determination of sulfamethoxazole in tablets
Ning Zheng1, Yuan-Zong Li, Mei-Juan Wen
1Laboratory Bioorganic & Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University Beijing 100871, China.
Journal of Chromatography. A
|April 10, 2004
Abstract:
A sulfamethoxazole (SMO)-imprinted polymer (MIP) was prepared in acetonitrile using the mixture of acrylamide and 4-vinylpyridine as functional monomers. The molecular recognition properties of the polymer was evaluated in both acetonitrile and aqueous acetonitrile mobile phases. SMO contents in two kinds of tablets were determined satisfactorily using the MIP packed HPLC column with aqueous mobile phase.
