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Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C (UV-C) Damage
Published on: February 15, 2020
Sunlight and age-related eye disease
1Department of Anatomy and Cell Biology, Jules Stein Eye Institute, Los Angeles, California.
Journal of the National Medical Association
|April 1, 1992
Summary
Protecting eyes from UV and blue light with sunglasses can prevent vision loss from age-related macular degeneration and cataracts. This simple measure can significantly delay or eliminate these common causes of visual impairment in older adults.
Area of Science:
- Ophthalmology
- Gerontology
- Preventive Medicine
Background:
- Age-related macular degeneration and cataracts are projected to affect 50 million elderly Americans within 50 years.
- These conditions are consequences of normal aging, exacerbated by environmental factors.
- Ocular deterioration is linked to oxygen, heat, and solar radiation exposure.
Purpose of the Study:
- To identify practical preventive measures against age-related visual impairment.
- To assess the impact of solar radiation on ocular health.
- To propose a method to delay the onset of macular degeneration and cataracts.
Main Methods:
- Review of evidence on causes of ocular deterioration.
- Analysis of the effects of ultraviolet (UV) and high-energy visible (blue) light on the eye.
- Evaluation of the protective potential of UV-blocking and light-attenuating sunglasses.
Main Results:
- Solar radiation, specifically UV and blue light, significantly contributes to lens and retinal damage.
- Sunglasses blocking UV radiation and attenuating blue light can slow ocular deterioration.
- A 20-year delay in disease onset could virtually eliminate these conditions as major causes of visual impairment.
Conclusions:
- Sunglasses offer a simple, safe, and inexpensive method to prevent age-related visual impairment.
- Widespread use of protective eyewear can mitigate the impending crisis of vision loss in the elderly.
- Delaying the onset of macular degeneration and cataracts through light protection is a feasible public health strategy.
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