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The correlation between plasma homocysteine and malondialdehyde levels in preeclampsia
Niyazi Tug1, Husnu Celik, Gurkan Cikim
1Obstetrics and Gynecology Department, Firat University School of Medicine, Elazig, Turkey.
Objective:
To investigate the possible correlation between plasma malondialdehyde and homocysteine levels of preeclamptic patients.
Design:
Venous blood samples of 20 preeclamptics and 20 healthy pregnant controls were collected. Plasma malondialdehyde and homocysteine concentrations were measured and the correlation between them was investigated. Mann Whitney U test and Spearman correlation analysis were used for statistical analysis.
Setting:
University of Firat, Medical School.
Results:
Plasma malondialdehyde and homocysteine concentrations were higher in preeclamptic patients (p<0.05) and a positive correlation between these parameters was found (r: 0.77, p<0.01, n:20).
Conclusion:
Our results may put forward some new strategies in the research of etiopathogenesis and treatment of preeclampsia.
