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Published on: April 3, 2026
[Large retroperitoneal malignant fibrohistiocytoma: report of one case]
José Miguel Giménez Bachs1, Antonio Salinas Sánchez, Juan Lorenzo Romero
1Servicio de Urología, Complejo Hospitalario Universitario de Albacete, Albacete, España. gbjosem@sescam.jccm.es
Objectives:
To report one case of a large retroperitoneal malignant fibrohistiocytoma.
Methods/Results:
40-year-old female with the diagnosis of a large right retroperitoneal mass after a study for right flank pain and weight loss over several months. Surgery was performed with excision of a large tumor; the pathologic diagnosis was malignant fibrohistiocytoma.
Conclusions:
Primary retroperitoneal tumors are rare neoplasias, usually diagnosed in advanced stages. The malignant fibrohistiocytoma is an infrequent entity with difficult histological diagnosis and poor prognosis. To date, the only valid option is surgery, because adjuvant treatments do not offer clear advantages today.