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Updated: Jul 25, 2026

Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice
Published on: July 25, 2014
Approaches to transplantation tolerance in humans
Samuel Strober1, Robert J Lowsky, Judith A Shizuru
1Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305-5166, USA. sstrober@stanford.edu
Abstract:
Although transplantation tolerance to organ allografts has been achieved using a wide variety of immunologic interventions in laboratory animals, few tolerance induction protocols with complete immunosuppressive drug withdrawal have been tested in humans. Preclinical and clinical studies of the use of total lymphoid irradiation for the induction of chimeric and nonchimeric tolerance are summarized here.
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