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Updated: Aug 24, 2026

Efficient and Scalable Directed Differentiation of Clinically Compatible Corneal Limbal Epithelial Stem Cells from Human Pluripotent Stem Cells
Published on: October 24, 2018
Stem cell therapy for ocular disorders
Leonard A Levin1, Robert Ritch, Julia E Richards
1Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792-4673, USA.
Abstract:
Cell injury or degeneration occurs in a number of blinding diseases. Therapy has classically consisted of preventing the initial injury or increasing the resistance of cells to injury (cytoprotection). Recently, it has become possible to repopulate tissue compartments with stem cells. This article presents a current summary of ocular stem cell research and applications to disease. It is based on presentations and discussions from the July 2002 international conference "Stem Cells and Glaucoma" sponsored by the Glaucoma Foundation. This meeting, the first of its kind, brought together ophthalmologists, geneticists, immunologists, and developmental biologists working on stem cell development and applications in both human and animal models.
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