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Updated: Aug 24, 2026

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
Published on: October 14, 2016
[JT interval changes in acute myocardial infarction following coronary angioplasty]
Gediminas Jarusevicius1, Ramūnas Navickas, Alfonsas Vainoras
1Institute of Cardiology and Clinic of Cardiology, Kaunas University of Medicine, Sukileliu 17, 3007 Kaunas, Lithuania. gedijaru@takas.lt
Insights
Early reperfusion positively impacts ventricular repolarization in acute myocardial infarction patients. This study observed changes in JT interval and JT dispersion following percutaneous transluminal coronary angioplasty.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Acute myocardial infarction (AMI) is a critical condition requiring prompt intervention.
- Percutaneous transluminal coronary angioplasty (PTCA) is a primary treatment for AMI.
- Ventricular repolarization, assessed by the JT interval, is crucial for cardiac health.
Purpose of the Study:
- To investigate the effect of early reperfusion on JT interval behavior in AMI patients.
- To analyze changes in JT interval and JT dispersion (JTd) after PTCA.
Main Methods:
- 14 patients with AMI underwent coronary angiography and PTCA.
- 12-lead surface electrocardiograms were recorded using "Kaunas-Load" equipment.
- Measurements were taken before PTCA, and at 5 minutes and 24 hours post-procedure.
Main Results:
- Immediately after PTCA, significant shortenings in JT interval and JTd were observed.
- A prolongation of both JT and JTd intervals was noted in all patients after 24 hours.
Conclusions:
- Changes in repolarization during PTCA may be linked to myocardial ischemic injury.
- Early reperfusion demonstrates a beneficial effect on ventricular repolarization dynamics.
Objective:
The aim of the study was to determine the influence of early reperfusion on the behavior of JT interval in patients with acute myocardial infarction undergoing percutaneous transluminal coronary angioplasty.
Material And Methods:
Coronary angiography and percutaneous transluminal coronary angioplasty were done for 14 acute myocardial infarction patients. Measurements were performed from 12-lead surface electrocardiogram with "Kaunas-Load" equipment before percutaneous transluminal coronary angioplasty, 5 minutes and 24 hours after it.
Results:
Immediately after percutaneous transluminal coronary angioplasty there were shortenings of JT and JT dispersion (JTd) and after 24 hours in all the patients prolongation of JT and JTd intervals was observed.
Conclusions:
Changes of the repolarization during percutaneous transluminal coronary angioplasty could be related with ischemic myocardial lesion. Early reperfusion has positive impact on the ventricular repolarization.
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