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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
[The treatment of lung cancer relapse after the lung resection]
Algirdas Jackevicius1, Saulius Cicenas, Dainius Amerigas Piscikas
1Institute of Oncology, Vilnius University, Santariskiu 1, 2021 Vilnius, Lithuania. algirdasj@is.lt
Unlabelled:
The aim of the study was to analyze the patients with the relapse of tumors after lung resection.
Material And Methods:
One hundred eight patients with lung cancer were operated at Lithuanian Institute of Oncology during period of 1992-2002. To 28 patients pneumonectomy was performed, 4 - bilobectomy, 51 - lobectomy, 23 - wedge resection, 2 - segmentectomy. According to the stage of tumor operations more often were performed in III stage of the disease - to 62 patients, in II - 20, in I - 12 and in the IV - 14. The most common histologic type of tumor was squamous cell carcinoma - 57 patients, adenocarcinoma - 29, small cell carcinoma - 12, anaplastic carcinoma - 4, other types of tumor were rare. The stage of disease had influence upon the time for the relapse of tumor. The dissemination of tumor was detected in 9 patients with II ir III stage of disease. The treatment of the relapse of lung tumor was the following was: 31 patients received radiotherapy, 4 - photodynamic therapy, 12 - radiotherapy with chemotherapy, 20 - chemotherapy.
Results:
According to the data of March 31, 2003, 98 patients died from carcinoma, 10 patients lived with the signs of disease. Median survival after relapse of tumor was better in patients with I stage of disease - 26.2 months, II - 20.7 months, III - 13.9 months, IV - 8.2 months.
Conclusions:
In the case of locally extended tumor with metastases in regional lymph nodes after lung resection the relapse of tumor was most common. The treatment of the relapse of tumor in early stages of disease was most effective.