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Updated: Aug 24, 2026
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
[Combined treatment for pain from bone metastases in patients with prostate cancer]
Xiaomin Ren1, Jun Ying, Dehong Yao
1Department of Urology, Shanghai Ninth People's Hospital Affiliated to Shanghai Second Medical University, Shanghai 200011, China. renxmb@online.sb.cn
Objective:
To evaluate the effects of combined treatment of hormone therapy with strontium-89 for pain from bone metastases in patients with prostate cancer.
Methods:
Sixteen patients with metastasis prostate cancer received hormone therapy with strontium-89 chloride (89Sr), and 4 of them received radiotherapy.
Results:
The pain was relieved. Relief occurred in 75.6% of the patients for 3 months, 80.5% for 6 months and 63.4% for 9 months.
Conclusion:
Hormone therapy enhances the effect of 89Sr without obvious toxicity. The combined treatment not only significantly raises pain palliation, prolongs pain-free survival, but improves the patients life quality.
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