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Rosai--Dorfman disease with multi-organ involvement in head and neck region

O Faruk Unal1, Elif Gülin Koçan, Arzu Sungur

  • 1Department of Otolaryngology Head and Neck Surgery, Medical Faculty, Hacettepe University, Ankara, Turkey. ofunal@tr.net

International Journal of Pediatric Otorhinolaryngology
|April 15, 2004
PubMed

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Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...