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Updated: Aug 24, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Diterpenoids from Calceolaria inamoena
Juan A Garbarino1, María Cristina Chamy, Marisa Piovano
1Departamento de Química, Universidad Técnica Federico Santa María, Casilla 110-V, Valparaíso, Chile. juan.garbarino@usm.cl
Abstract:
Four 9-epi-ent-labdanes were isolated from the aerial parts of Calceolaria inamoena. Their structures, 2beta-hydroxy-9-epi-ent-labda8(17)-13(E)dien-15-oic acid, 2beta-hydroxy-9-epi-ent-labda8(17)-13(Z)dien-15-oic acid, 2beta-hydroxy-9-epi-ent-labda8(17)-13(E)dien-15-al and 2beta-hydroxy-9-epi-ent-labda-8(17)-13(Z)dien-15-al, were established by spectroscopic methods including by analysis of 2 dimensional heteronuclear correlation experiments 1H/13C (normal and long range), and NOE and gs-sel-1D-NOESY and TOCSY of their methyl ester or acetyl derivatives.
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