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Updated: Aug 24, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
Published on: November 3, 2023
Effects of hypertonic dextran in hypovolaemic shock: a prospective clinical trial
Emin Kaya Alpar1, Vijay Vardhan Killampalli
1Department of Trauma and Orthopaedic Surgery, University Hospital Selly Oak NHS Trust, Raddlebarn Road, Birmingham B29 6JD, UK. alpar.med@btinternet.com
Abstract:
The aim of this paper is to report the results of prospective clinical trials of hypertonic saline dextran (HSD) in the resuscitation of hypovolaemic shock in critically injured patients. There are many types of fluids, which can be administered intravenously. Recent interest in the usage of HSD solution has confirmed that they have a place in resuscitation of a patient in shock. Heart rate and arterial pressure recovered well with HSD solution. The plasma osmolarity, sodium and potassium levels were significantly elevated in patients resuscitated with HSD. Urine output recovered rapidly and was well maintained throughout.
