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Updated: Jul 30, 2026
17:16
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
Published on: December 9, 2010
Nanomedicines for overcoming biological barriers
1Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Santiago de Compostela 15782, Spain. ffmjalon@usc.es
Summary
This review highlights advances in nanomedicines for mucosal drug delivery. Nanosystems protect drugs, enhance transport across barriers, and enable controlled release for more effective medicines.
Area of Science:
- Drug delivery and nanomedicine research.
- Development and characterization of nanocarriers for mucosal administration.
Background:
- Drug delivery research focuses on enabling new drugs and improving existing ones.
- Nanomedicines utilizing nanosystems are a key area for targeted drug delivery.
Purpose of the Study:
- To review advances in developing and characterizing nanosystems for mucosal drug delivery.
- To discuss nanocarriers' ability to protect drugs, cross barriers, and control release.
Main Methods:
- Review of nanotechnologies for drug association with nanocarriers.
- Evaluation of nanocarrier materials (polymers, lipids, polysaccharides).
- In vitro and in vivo studies assessing barrier penetration and drug delivery efficacy.
Main Results:
- Nanosystems demonstrate potential for protecting drugs from degradation.
- Nanocarriers facilitate drug transport across intestinal, nasal, and ocular mucosal barriers.
- Controlled drug release to target tissues is achievable with some nanocarriers.
Conclusions:
- Developed nanocarriers show promise for overcoming mucosal barriers.
- Safe materials are used in nanocarrier construction.
- This technology could lead to more efficacious, cost-effective medicines.
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