Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pertussis in Poland.

Anna Gzyl1, Ewa Augustynowicz, Daniel Rabczenko

  • 1Department of Sera and Vaccines Evaluation, National Institute of Hygiene, 24 Chocimska Str., 00-791 Warsaw, Poland. agzyl@pzh.gov.pl

International Journal of Epidemiology
|April 15, 2004
PubMed
Summary

Pertussis (whooping cough) incidence increased in Poland despite high vaccination rates. Waning immunity and potential vaccine escape mutants may be driving this resurgence, particularly in older children and adolescents.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Obesity and Beyond: Lifestyle Patterns and Cardiometabolic Burden in High-Risk Patients with Coronary Artery Disease-Moving Toward Personalized Prevention.

Diseases (Basel, Switzerland)·2026
Same author

Impact of an Enhanced Disinfection Protocol on the Incidence of <i>Clostridioides difficile</i> Infections and Antibiotic Consumption in a Hospital Setting: A Retrospective Intervention Study.

Journal of clinical medicine·2025
Same author

First-in-human study of CPL'116 - a dual JAK/ROCK inhibitor - in healthy subjects.

Frontiers in pharmacology·2025
Same author

[The changing epidemiology of tick-borne encephalitis: epidemic surveillance and disease prevention challenges].

Medycyna pracy·2024
Same author

The protective effect of a new absorbent incontinence design against an alkaline pH challenge on the epidermal barrier.

Wound management & prevention·2024
Same author

Improving Vaccine Assessment Pathways and Decision Making in the Polish Immunization Program.

Vaccines·2024

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Vaccinology

Background:

  • Pertussis (whooping cough) incidence saw a 2-5 fold increase in Poland since 1997, contrasting with a 100-fold reduction in the 1980s following diphtheria-tetanus-pertussis (DTP) vaccination.
  • This resurgence occurred despite stable vaccination coverage, prompting an investigation into potential contributing factors.

Purpose of the Study:

  • To analyze pertussis data in Poland to identify risks associated with its re-emergence.
  • To understand shifts in pertussis epidemiology, including age-specific incidence and geographical distribution.

Main Methods:

  • Data on pertussis notification, incidence, mortality, and hospitalization were collected from national surveillance monographs.
  • Statistical evaluation of available pertussis data, including geographical and age-specific incidence, was performed.

Related Experiment Videos

Main Results:

  • Two distinct trends of rising and falling pertussis incidence were observed, with a shift around 1989.
  • After 1989, incidence decreased in children aged 0-4 years but increased in those aged 5-19 years. Infant incidence remained stable.
  • Pertussis incidence increases showed a geographical clustering pattern from Northeast to Southwest Poland.

Conclusions:

  • Waning immunity and potential Bordetella pertussis vaccine escape mutants are suspected causes for the changing epidemiological parameters.
  • Improved diagnostics and continued monitoring are recommended for more precise data collection.
  • A booster dose of acellular pertussis vaccine at age 6 has been added to the vaccination schedule.