Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Gas Exchange and Transport

Gas Exchange and Transport

Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.

Physiological Control of Respiration

Physiological Control of Respiration

Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...

Respiratory Assessment: Purpose and Indications

Respiratory Assessment: Purpose and Indications

Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...

Physiology of Respiration I: Functions of the Respiratory System

Physiology of Respiration I: Functions of the Respiratory System

The respiratory system is crucial for exchanging oxygen (O2) and carbon dioxide (CO2) between the atmosphere and the bloodstream, maintaining the body's balance. Beyond gas exchange, it helps regulate acid-base balance, purify inhaled air, and enable vocalization.
Fundamental Processes in Respiration:

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...

Administering Oxygen by Mask

Administering Oxygen by Mask

Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sexual Dimorphism in Plantar Pressure Distribution Patterns.

Physiological research·2025

Same author

Virtual Reality-Based Rehabilitation Therapy.

Physiological research·2025

Same author

A wise person plants a tree a day before the end of the world: coping with the emotional experience of climate change in Poland.

Current psychology (New Brunswick, N.J.)·2022

Same author

Isotonic Saline Nebulization and Lung Function in Children With Mild Respiratory Ailments.

Physiological research·2020

Same author

Clinical Significance of Gastrointestinal Carriage of Klebsiella Pneumoniae-Producing Extended-Spectrum Beta-Lactamases in Kidney Graft Recipients.

Transplantation proceedings·2018

Same author

Systolic myocardial volume gain in dilated, hypertrophied and normal heart. CMR study.

Clinical radiology·2017

Search research articles

Related Experiment Video

Updated: Jun 30, 2026

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents

Published on: July 9, 2020

Oxygen breathing and ventilation.

M Marczak¹, M Pokorski

¹Department of Respiratory Research, Medical Research Center, Polish Academy of Sciences, Warsaw, Poland. mpokorski@cmdik.pan.pl

Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society

|April 15, 2004

Summary

This summary is machine-generated.

Breathing pure oxygen initially decreases ventilation in healthy individuals but then increases it. This suggests acute oxygen therapy may not significantly inhibit the carotid body

More Related Videos

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Published on: December 5, 2025

Related Experiment Videos

Last Updated: Jun 30, 2026

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents

Published on: July 9, 2020

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Published on: December 5, 2025

Area of Science:

Physiology
Respiratory Medicine

Background:

The ventilatory response to hyperoxia is complex and not fully understood.
Investigating the impact of acute oxygen administration on breathing regulation is crucial for clinical practice.

Purpose of the Study:

To examine the ventilatory response to normobaric poikilocapnic hyperoxia in healthy subjects.
To determine if acute oxygen breathing inhibits carotid body-dependent ventilatory drive.

Main Methods:

26 healthy subjects breathed pure oxygen for 10 minutes.
Ventilation, oxygen saturation (SaO2), and end-tidal carbon dioxide (PaCO2) were monitored.
A control group breathed room air.

Main Results:

Oxygen breathing caused an initial transient 8.4% decline in ventilation.
Ventilation then significantly increased above baseline levels.
A rising tendency in ventilation was observed towards the end of the test.

Conclusions:

Acute oxygen treatment is unlikely to significantly inhibit carotid body-dependent ventilatory drive in healthy individuals.
Further studies are needed to elucidate the mechanisms driving hyperoxic ventilatory stimulation.